One spray, five kinds of wound.
From diabetic foot ulcers to deep venous wounds and everyday cuts — where Exonira fits, how it is used, and how strong the evidence is for each.
Where it fits.
Each wound heals differently. Select one to see the challenge, standard care, Exonira’s intended role and an honest evidence label.
Diabetic foot ulcers
Nerve damage hides pain, circulation is reduced, and infection can take hold quickly — so diabetic foot ulcers heal slowly and recur.
Applied once daily as a no-touch spray over the cleaned ulcer bed, alongside standard care.
- Off-loading of pressure
- Debridement of dead tissue
- Infection control
- Moisture-balanced dressings
- Blood-sugar and circulation management
A 30-subject, 90-day, open-label study in Wagner grade ≤ 2 ulcers reported significant improvement in ulcer area, wound evaluation and function (p < 0.05) with no adverse events. Small, non-randomised, no comparator.
Varicose & venous ulcers
Failing valves in the leg veins let blood pool, raising pressure in the skin until it breaks down; these wounds are often deep, wet and slow.
Sprayed over the cleaned wound bed and surrounding skin, then covered with the dressing the clinician has chosen.
- Compression therapy (when arterial supply allows)
- Leg elevation and walking
- Treating the underlying venous disease
- Cleaning and exudate-managing dressings
The product literature lists varicose and chronic venous ulcers as intended uses, and individual case photographs exist. There is no controlled study in this group — treat evidence as case-level only.
Venous disease & post-thrombotic wounds
After a deep-vein thrombosis the veins can stay damaged, leaving swollen legs and stubborn skin ulcers. Anticoagulant medicines also make wounds bleed more easily.
Exonira is for the skin wound only. It does not treat a clot, and does not replace anticoagulant or vascular care. Use should be agreed with the treating clinician.
- Medical management of the clot and its risks
- Compression and elevation as advised
- Careful wound cleaning and dressing
- Specialist review of persistent ulcers
No study of Exonira in thrombosis-related wounds is available. Any role is by formulation rationale and clinician judgement only.
Deep & non-healing wounds
Deep wounds need to fill from the base upward. Dead tissue, bacteria and poor blood flow can stall the process for months.
Spray to cover the entire wound bed, make sure the wound is clean and drained first, let it dry, then dress. Avoid use on highly inflamed, heavily weeping areas.
- Debridement and cleaning
- Packing or dressing the full depth
- Infection control and, if needed, antibiotics
- Off-loading and nutrition
- Specialist or surgical review
Chronic non-healing wounds are an intended use in the product literature; formal data are for diabetic foot ulcers. Deep wounds with exposed bone or tendon, abscess or spreading infection need urgent medical care first.
Accidental & incidental wounds
Everyday cuts, scrapes and abrasions mostly heal on their own; the aim is a clean, protected wound-bed.
The label lists minor wounds among intended uses: clean the area, spray, let dry, and cover as needed.
- Stop bleeding with pressure
- Rinse with clean water or saline
- Protect with a clean dressing
- Check tetanus status for dirty or deep cuts
No clinical study in minor wounds. Seek care for deep, gaping, bleeding-that-won’t-stop, bitten, or contaminated wounds.
Four phases, one pathway.
Healing follows the same sequence in most wounds; chronic wounds tend to stall in the inflammatory phase.
Haemostasis
Minutes. Bleeding stops as a clot forms. Pressure and clinical care — not a topical — control bleeding.
Inflammation
Days 1–4. The wound is cleared of debris and bacteria. In chronic wounds this phase can persist.
Proliferation
Days 4–21. New tissue and vessels fill the wound from the base up.
Remodelling
Weeks to months. The scar matures and strengthens.
Exonira’s botanicals are described in the formulation rationale as supporting cleansing, anti-inflammatory balance, fibroblast and epithelial activity, and collagen support. This is rationale for study, not proof of effect in every phase.
What is known, and what is not.
A plain statement of the evidence for each use.
| Use | Status | What exists |
|---|---|---|
| Diabetic foot ulcers | Clinical study | 30-subject, 90-day open-label study (Wagner ≤ 2); in-vitro antimicrobial and cell-migration data |
| Varicose & venous ulcers | Case documentation | Individual case photographs; no controlled study |
| Post-thrombotic wounds | Rationale only | No study; skin-wound care only, never a clot treatment |
| Deep non-healing wounds | Rationale only | Intended use in product literature; formal data are in DFU |
| Accidental & minor wounds | Rationale only | Labelled use; no clinical study |
Four steps, no touch.
Hold the spray 4–6 inches away at about 45° and cover the whole wound bed and surrounding skin — once daily, or as directed by your physician.
Clean
Rinse gently with saline; pat dry.
Spray
Cover the wound bed and surrounding area evenly.
Dry
Let it dry fully before dressing.
Cover
Apply a sterile dressing or gauze.
Do not wait. Get help now if…
- The calf or leg is suddenly swollen, painful, warm or red — possible deep-vein thrombosis
- Chest pain or breathlessness — possible pulmonary embolism: call emergency services
- Spreading redness, pus, a foul smell, fever or chills
- Black or dead-looking tissue, or bone or tendon visible in the wound
- Bleeding that will not stop with firm pressure
- A wound that is not improving, or is getting larger or more painful
Exonira is a topical, external-use product — not a substitute for medical advice, debridement, off-loading, vascular care or infection treatment. Avoid use on highly inflamed areas with excessive fluid; consult a practitioner if pregnant or nursing; keep away from the face and out of children’s reach.
Clear answers.
Is Exonira a treatment for thrombosis?
No. Exonira is a topical spray for the skin wound. It does not treat a blood clot, and suspected thrombosis needs urgent medical assessment. Use alongside any anticoagulant care only as agreed with your clinician.
Can it be used on deep wounds?
It is intended as an adjunct on chronic and non-healing wounds. The wound should be clean and properly drained; deep wounds with exposed structures, abscess or spreading infection need clinical care before any topical product.
Does it stop bleeding?
Do not rely on Exonira to control bleeding. Apply direct pressure and seek care if bleeding does not stop.
How long should it be used?
Once daily, or as directed by a physician. The diabetic-foot-ulcer study applied it for 90 days under clinical supervision.
Where is the evidence strongest?
In diabetic foot ulcers (Wagner grade ≤ 2), from a 30-subject open-label study. For other wound types the evidence is case-level or based on formulation rationale — which is why we label it for each indication below.
Bring Exonira to your clinic or pharmacy.
Hospitals, wound clinics, pharmacies and distributors — tell us your region and volumes.